Encoded combinatorial chemistry.

Combinatorial chemistry

Combinatorial chemistry, which did not even exist fifteen years ago, is a new subfield of chemistry that is starting to provide insights into molecular interactions, biochemical catalysis and drug development. Instead of finding and testing naturally existing compounds for useful activity, the basic aim of combinatorial chemistry studies is to create vast numbers of new, synthetic compounds and...

Combinatorial chemistry.

Concepts of Combinatorial Chemistry and Combinatorial Technologies

Combinatorial Chemistry and Combinatorial Technology (CC/CT) are a new interdisciplinary field joining computerassisted combinatorial chemistry with automated parallel synthesis of chemical ìlibrariesî followed by automated screening. The main purpose of computer assisted combinatorial chemistry is to generate thousands structurally diverse compounds as libraries, maximising their diversity, wh...

A composite element bit design for magnetically encoded microcarriers for future combinatorial chemistry applications

We present a new composite element (CE) bit design for the magnetic bit encoding of suspended microcarriers, which has significant implications for library generation applications based on microfluidic combinatorial chemistry. The CE bit design consists of high aspect ratio strips with appropriate dipolar interactions that enable a large coercivity range and the formation of up to 14 individual...

Encoding strategies in combinatorial chemistry.

To Pasteur’s famous dictum, ‘‘Chance favors the prepared mind,’’ could arguably be added the corollary, ‘‘As the number of chances increases, so increases the effect of favor.’’ It is nearly a truism that a great many important discoveries in chemistry originated not from careful design, but from astute observations of unintended experiments. Suppose, then, that creativity were applied to the t...